The Coley Campaign
Throughout the literature of cancer past and present, only a few intervening variables have been consistently associated with durable remissions. Durability is the holy grail of remission — lasting remission. As Matzinger has pointed out, surgery, bacterial infections, and bacterial vaccines are variables associated with durable “spontaneous” remissions from malignant diseases. Coley Fluid is one of those variables, and it is our opinion that the federal government should be on the hook for funding and executing long neglected basic and translational investigations into the mechanisms of this seminal method of cancer management.